For business - When I'm working in London, I stay at the October Gallery in Old Gloucester Street. It's an old Victorian schoolhouse run by a lady called Chili - a glamorous version of Meryl Streep. There's the gallery, courtyard and a big club room with a grand piano and a giant library - great for holding launches or just having damn good parties. You never know who'll be there. You make your own breakfast and there's fabulous home-made muesli. The cooking is also fabulous, usually oriental. The rooms are covered in art, with deep crimson sheets and comfy pillows. The shared bathroom has 'big water'. Big water and comfy pillows are all you need for a great hotel.
For pleasure - L'Hotel des Deux Clefs is in Turckheim - an amazing, perfectly preserved medieval village in Alsace, France. The nearest town is an ugly industrial town called Colmar, so it's an extraordinary juxtaposition. It's on the border, so the hotel has Germano-French cuisine - very grand and all local produce such as wild boar and dill berries. The rooms are huge with great big beds, and the furniture is crazy. The water is amazing - if you bathe in it you fall straight asleep. There are vines inside the courtyard that you can eat grapes off, big oak beams and window boxes with geraniums and nasturtiums - very chocolate-boxy. It reeks of old age and comfort. I've recommended it to lots of people - they all say it's the finest hotel they've stayed in.